11 articles - From Friday May 20 2022 to Friday May 27 2022
Guidelines, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Liver Transpl |
Donor eligibility criteria and liver graft acceptance criteria during normothermic regional perfusion: a systematic review. One-year graft and patient survival were 75% (66-82%) and 82% (75-88%) in uDCD and 91% (89-93%) and 93% (91-94%) in cDCD respectively. In conclusion, the currently used assessment criteria consist of macroscopic aspect and transaminase levels. The acceptance criteria should be tailored according to donor type to prevent an unacceptable PNF rate in uDCD and to increase the relatively modest Organ Utilization Rate in cDCD. |
RCT, clinical trials, retrospective studies, etc…
| Liver Transpl |
The Impact of Human Leukocyte Antigen Mismatch on Recipient Outcomes in Living-Donor Liver Transplantation. Notably, a total of = |
Utilization of pre-procurement biopsy in donation-after-circulatory death (DCD) liver transplantation. Biopsy excluded 6.6% of DCD donor livers for transplant prior to recovery and facilitated the successful recovery and transplant of two-thirds of potential DCD donor livers. Livers intended for transplant at the time of recovery that did not undergo pre-procurement biopsy were more likely to not be recovered or to be discarded. Pre-procurement biopsy provides additional histologic information prior to deploying resources, and helps to identify usable livers that might otherwise be declined for transplant. Consideration of liver biopsy in this group benefits OPOs and transplant centers by maximizing organ utilization and optimizing resource deployment. |
| Pancreatology |
Extracellular vesicle-derived microRNAs in pancreatic juice as biomarkers for detection of pancreatic ductal adenocarcinoma. The potential to detect PC was good for a combination of PJ EV-miR-21, EV-miR-25, EV-miR-16 and serum miR-210, CA-19-9, with an area under the curve of 0.91, a specificity of 84.2% and a sensitivity of 81.5%. Detection of miRNA from EVs in PJ is feasible. A combined panel of PJ EV-miR-21, EV-miR-25, EV-miR-16, and serum EV-miR-210 and CA19-9 distinguishes cases with PDAC from controls undergoing surveillance with a specificity of 81.5% and sensitivity of 84.2%. |
Impact of tumor size and location on endoscopic ultrasound-guided sampling of pancreatic neuroendocrine tumors: A recursive partitioning analysis. In 41 patients with a pNET size less than 18.5 mm, the EUS-guided first biopsy was successful in 90.2%. In 16 of these patients with smaller lesions, EUS-guided sampling was 100% in very small (less than 11 mm) and extremely small lesions (less than 8 mm). The biopsy success rate was 100% in tail lesions in the size range between =5.95 and <8.1 mm but only 33.3% independent of the investigator in pancreatic head or body, with an error rate of 11.2% CONCLUSION: Using a recursive partitioning of the tree-aided stratification model, we demonstrate for the first time that in balancing risks and benefits, very small pNETs (<1 cm) in the tail of the pancreas should be sampled under EUS-guidance. |
Variants in the pancreatic CUB and zona pellucida-like domains 1 (CUZD1) gene in early-onset chronic pancreatitis - A possible new susceptibility gene. Our data indicate that CUZD1 might be a novel susceptibility gene for NACP. How these variants predispose to pancreatitis remains to be elucidated. |
Plenty of the editorials are available as full text through the publisher website using the provided link
Letters to the editors and authors’ replies
all remaining publications eg case reports, images of the month, etc…
| Am J Clin Nutr |
| Liver Transpl |